🦷 Breakthrough Dental Tech: IISc & Theranautilus Deploy Magnetic Nanobots Against Tooth Sensitivity

Bangalore, 2025 – In a world-first innovation, Indian Institute of Science (IISc) researchers and deep-tech startup Theranautilus have developed CalBots – microscopic magnetic robots that actively seek and seal exposed dentinal tubules, revolutionizing treatment for 1.5 billion people suffering from tooth sensitivity globally.

🔬 How CalBots Work

1️⃣ Guided Navigation

• 200nm-sized bots steered by external magnetic fields to precisely target tubules
• 10x more accurate than traditional desensitizing gels

2️⃣ Smart Sealing

• Carry biocompatible mineral nanocapsules (hydroxyapatite/fluoride)
• Release payload only on contact with dentin (pH-triggered)

3️⃣ Self-Destruct

• Dissolve into harmless ions after treatment

💡 Why This Disrupts Dentistry

🛠️ Development Journey

• 2019: IISc’s proof-of-concept (Science Robotics paper)
• 2022: Theranautilus spin-off (backed by C-CAMP & DBT)
• 2024: Completed large-animal trials (92% success rate)

🌍 Market Potential

• $18B global desensitizing products market
• Targets both clinics (in-office procedure) and OTC (future home kit version)

📅 Commercialization Path

• 2025: Seek CDSCO approval for human trials
• 2026: Partner with Dental chains (Clove Dental interested)
• 2027: Launch “Painless Pro” professional system ($5K/unit)

🧠 Expert Insight:
“This is microrobotics’ first practical application in dentistry – the start of a precision oral care revolution.”
—Dr. Debayan Dasgupta, Theranautilus CTO

📢 Would you volunteer for nanobot dental treatment?
#MedTech #Dentistry #Nanobots #IISc #DeepTech #HealthcareInnovation